Carglumic Acid can help to eliminate high ammonia levels in the blood. Ammonia is especially toxic for the brain and can lead, in severe cases, to reduced levels of consciousness and to coma.
High levels of ammonia in the blood may be due to:
• (N-acetylglutamate synthase). Patients with this rare disorder are not able to eliminate nitrogen waste, which builds up after eating protein. This disorder persists throughout the treatment.
• Isovaleric acidemia, methylmalonic acidemia or propionic acidemia. Patients suffering from one of these disorders need treatment during the hyperammonemia crisis.